Top 5 Nitric Oxide Supplements

What nitric oxide boosting supplement took home the Editor's Choice Award? We understand how important finding the best nitric oxide supplement is for you, to achieve the ultimate boost during your exercise regime and post workout, so to help you achieve extreme body changing results, we listed our top 5 nitric oxide boosting products. To come up with our top products, we evaluated scores of product options, from over the counter to all natural products. We listed them here in order of superiority and based our research on the following criteria:

  • 1) Performance*
  • 2) Speed of Results*
  • 3) Quality of Ingredients
  • 4) Product Safety
  • 5) Customer Service
  • 6) Customer Feedback
  • 7) Reorder Rate
  • 8) Return Policy
  • 9) Success Rate


Nitric Oxide Center Top 5 Rating


Nitric Oxide Premium Troxyphen Elite Ubervita ANS Mascugen
1 2 3 4 5
Price (1 bottle)
Price (6 bottles) Best Value
Overall Rating 99.40% 86.90% 78.90% 74.70% 68.00%
Speed of Results Extremely Fast Good Average Average Slow
Quality of Ingredients Premium Good Good Average Unknown
Customer Satisfaction Evaluation 99.20% 84% 76.20% 72% 66.30%
Safety Evaluation Safe for Use Safe for Use Safe for Use Safe for Use Safe for Use
Customer Service Rating
Reorder Rate Highest Good Good Average Average
Return Policy Risk Free Single Bottle Only Unclear Unclear Unclear
Success Rate 99.40% 82.10% 76% 73.20% 65%

Nitric Oxide Supplements For 2024

#1 Nitric Oxide Premium

Overall Rating: 99.40%

Nitric Oxide Premium Nitric Oxide Premium Learn More

Product Claims

Our top recommendation for an nitric oxide boosting supplement is Nitric Oxide Premium. This product is formulated from all natural ingredients and every ingredient has been researched and proven to provide the ultimate nitric oxide production boost for the ultimate workout pump and physique enhancing benefits. Nitric Oxide Premium is a product that works internally providing the ultimate amino acids (L-Arginine and L-Citrulline) for extreme nitric oxide production. It doesn't stop there, a synergistic blend of incredible natural proven ingredients further supports this process to provide a platform for increased nitric oxide production like nothing else out there on the market. Each capsule of the product contains the top clinically proven key ingredients for increasing the production of nitric oxide - L-Arginine Blend (4 types), L-Citrulline, Pine Bark, Quercetin, and Longjack, as well as BioPerine® for fast absorption. Furthermore, the L-Arginine in this supplement is an incredible blend of four subtypes, including AAKG (Arginine Alpha-ketoglutarate), MONO (L-Arginine Monohydrate), MALATE (L-Arginine Malate) and AKIC (Arginine Ketoisocaproate). L-Arginine is a precursor for the synthesis of nitric oxide, this powerful blend of L-Arginine subtypes provides the optimal benefit of this intense nitric oxide boosting amino acid. More importantly, there are no unwanted side effects from these ingredients.


Along with the great formula, Nitric Oxide Premium offers real value in the package deals. Nitric Oxide Premium offers a $220 discount if you order 6 bottles, this is an incredible saving. As effective long term muscle growth and maintenance takes time, this is a sensible cost effective option. Positive customer feedback and testimonials demonstrate the huge numbers of satisfied customers with a 98% approval rate. This is impressive. Those who want to build muscle, bulk up and push boundaries in terms of endurance and sports performance, can feel very confident in this nitric oxide boosting product as it offers a 100% money back guarantee. Nitric Oxide Premium is formulated in a laboratory setting, at a facility that is FDA-Approved and GMP certified. This means that the company is held to very strict standards and high quality assurance.


Of all the all-natural nitric oxide boosting products, Nitric Oxide Premium ranks the highest. Their formula has the most effective all-natural ingredients, with an incredible blend of four subtypes of L-Arginine and works more effectively than all of the other products - simple! It also offers a money back guarantee and excellent customer service. With all this going for it, it’s no surprise that Nitric Oxide Premium is the best product available for nitric oxide boost and is Nitric Oxide Center’s #1 choice.

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#2 Troxyphen Elite

Overall Rating: 86.90%

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Product Claims

Troxyphen Elite Advanced Formulation from truDERMA came in a close second. It claims to boost nitric oxide, build lean muscle and decrease body fat

Troxyphen contains some impressive key ingredients and blends. Their Nitric Oxide Boost Blend includes several forms of L-Arginine plus L-Citrulline.

However, some of the added ingredients (such as gelatin) were not suitable for vegetarians, vegans and those with meat allergies/intolerances.

We did note that it contained caffeine and green coffee extract. On their label, they also warn not to take this before going to bed. We felt that those people who workout in the evening may find sleeping an issue after taking this supplement.


We felt that Troxyphen didn't provide enough options for consumers to choose and tailor their order package. They offer a one time purchase price, with no savings for multiple bottle purchases.

We were unable to find a money back guarantee. This weakened the product for us.


Troxyphen were almost there with a top quality product but we felt that there were several key elements missing. The ingredients are natural and it contains the top key ingredients clinically proven effective for boosting nitric oxide. However, the addition of gelatin and caffeine brought with it negative concerns which lowered the product’s appeal for us. Also, the lack of multi bottle purchasing options, which in the long run, can lower the cost of each bottle by a considerable amount left us also feeling a little let down by this product.

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#3 Ubervita

Overall Rating: 78.90%

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Product Claims

UberNO2 use natural ingredients that they claim builds muscles fast


UberNO2 contains some impressive key ingredients namely L-Arginine, Citrulline Malate, and Beetroot. However, the L-Arginine it contains only provides 2 subtypes as oppose to our top product which provided 4, therefore, because it is all about the ultimate boost, we felt this lowered the effectiveness of the product. The manufacturer also considered the wider market too, by making their capsules vegan friendly, gluten free and Kosher and Halal safe.


We felt that UberNO2 offered a good range of options for the consumer for multi bottle purchase, but there wasn't a clear money back guarantee, we think that consumers can’t feel totally confident to place an order without experiencing problems. They are a US based manufacturer.


UberNO2 offers a few very positive elements. The ingredients are spot on however, the addition of several subtypes of L-Arginine would increase the quality of this product. We like the fact they operate within the US and therefore fall under the FDA operating regulations but would benefit from offering a clear money back guarantee. Overall, more benefits than negatives.

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#4 ANS

Overall Rating: 74.70%

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Product Claims

ISO N.O. is produced by ANS Labs designed to increase blood flow, vascularity and endurance.

The ingredients are mainly natural and offered as a ‘Nitro-Vascular ‘Blend’. This sounds good, especially when it contains L-Arginine and L-Citrulline. However, we remain unclear exactly how much dosage of the blend lends itself to these amino acids versus the other less effective ingredients. For all we know, there could be minute ineffective doses of the key ingredients and huge amounts of the other less effective ones. We therefore have to trust the manufacturers that they made a decent product, but we can't be sure. This raised concerns for us as to the effectiveness of this product.

Although the company is well established, we could not properly establish a good level of customer feedback due to the limited reviews of the product we found. This could suggest that the product's effectiveness is weak or something else that we were unable to explain.


We felt that the price of $84.99 was very expensive for this product. Although, they do offer free 2-day shipping and a member discount through GNC.


With the lack of reviews and the unclear breakdown of the ingredients contained within the blend, together with the inflated price we placed this product in our # 4 ranking. Its regaining features however, include the fact that they use all natural ingredients plus it does contain L-Arginine and L-Citrulline, oh, and that it’s sold in GNC, so its easy to get if you run out!

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#5 Mascugen

Overall Rating: 68.00%

Mascugen Mascugen Learn More

Product Claims

Our #5 pick is Mascugen. It is claimed to boost nitric oxide and testosterone, muscle growth, male drive, energy and libido.

All ingredients it said to be natural and a ‘bio-product’. We found the inclusion of a good blend of amino acids - L-Arginine. However, that was it. There was no other herbal, vitamin or mineral backup. This definitely weakened the product for us, which was a shame because they had a good base start.

Another minus was the fact that it is offered in a gelatine capsule. This is a big negative for vegans, vegetarian, some religious groups and meat sensitive consumers.

This company includes testimonials, but only two! Its not enough for us to ascertain whether consumers are happy with this product.


This company do offer a 60 money back guarantee. This is a positive element. Plus, they offered several bulk buy options that provide discounted rates.


This product has some good points, the main base key ingredients are excellent. However, it needed more, it was almost like the ingredients list was incomplete. The fact that this contains gelatin was a big minus. Together with its limited customer reviews we had to place this at the bottom of our top picks. However, we liked the fact they have a money back guarantee and that customer satisfaction is important to them.

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